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» LAP-BAND Weight-Loss Liked To Over 70% Reduced Risk Of Death In People With Severe Obesity
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LAP-BAND Weight-Loss Liked To Over 70% Reduced Risk Of Death In People With Severe Obesity

Severely obese people who received the LAP-BAND Adjustable Gastric Banding System to lose weight had a 72 percent reduction in their risk of dying compared to obese people who were not offered any specific weight-loss treatment, according to findings published in the December issue of the Annals of Surgery (1). The LAP-BAND System was approved in June 2001 by the U.S. Food & Drug Administration for weight reduction in severely obese adults.

"This research is critical because it shows that people with severe obesity, who are known to be at a much higher risk than the general population for dying prematurely, may be able to significantly decrease their risk with laparoscopic adjustable gastric banding," explains Dr. Paul O'Brien, FRACS a study author from the Monash University Centre for Obesity Research and Education (CORE) in Melbourne, Australia, head of the Centre for Bariatric Surgery in Melbourne and the National Medical Director for the American Institute of Gastric Banding in Dallas, Texas. "What is also particularly compelling is that this study shows it is possible to gain a significant survival benefit without the risks associated with more invasive bariatric surgical procedures, such as gastric bypass."

The study involved two groups of people who were between 37 and 70 years of age with a Body Mass Index (BMI) of 35 kg/m2 or greater: A LAP-BAND System group, which included 966 patients (average age 47, average BMI 45 kg/m2) and a previously established population-based cohort of 2119 people who were not offered any specific weight-loss treatment (average age 55, average BMI 38 kg/m2). There were four deaths (heart disease, cancer and suicide) in the LAP-BAND System group after a median follow-up of four years, vs. 225 deaths after a median follow-up of 12 years in the non-treated group. After statistically controlling for the differences in follow up time, sex, age and BMI, the hazard for death was 72 percent lower for LAP-BAND System patients compared to the non-treated group (hazard ratio for death: 0.28, 95% confidence interval: 0.10-0.85). LAP-BAND System patients lost an average of approximately 63 pounds 2 years after installation.

The very low death rate seen in the LAP-BAND System group, while good news, limited the study, making it difficult to precisely determine the magnitude of the effect of the procedure on improved survival. Also, there may have been unknown differences between the two groups that may have affected results. The new findings are consistent with those from other studies showing a reduced risk of death (~30% to 89%) associated with the weight loss following other forms of bariatric surgery (2,3,4,5,6).

About Obesity

In the United States, obesity is considered the second leading cause of preventable death (7). Further, research has shown that individuals with a BMI of 35 or more have a reduced life expectancy of nine to 13 years (8). A BMI of 35 or more translates to a weight of 200 pounds or more for a woman of average height (5' 4") when ideal weight at this height is considered to be 140 pounds, and to a weight of 250 pounds or more for man who is six feet tall when ideal weight for this height is considered to be 177 pounds.

About the LAP-BAND System

The LAP-BAND System was approved by the FDA in June 2001 for severely obese adults with a Body Mass Index (BMI) of 40 or more or for adults with a BMI of at least 35 plus at least one severe obesity-related health condition, such as Type 2 diabetes, hypertension and asthma. Used in more than 300,000 procedures worldwide, this simple reversible surgically implanted device has safely helped severely obese adults successfully achieve and maintain long- term weight loss.

The LAP-BAND System was developed to facilitate long-term weight loss and reduce the health risks associated with severe and morbid obesity. Unlike gastric bypass, it does not involve stomach cutting, stapling or intestinal re-routing (9,10). Using laparoscopic surgical techniques, the device is placed around the top portion of the patient's stomach, creating a small pouch. By reducing stomach capacity, the LAP-BAND System can help achieve long-term weight loss by creating an earlier feeling of satiety. The LAP-BAND System is adjustable, which means that the inflatable band can be tightened or loosened to help the patient achieve a level of satiety while maintaining a healthy diet. It is also reversible and can be removed at any time.

About True Results:

The American Institute of Gastric Banding is an industry-leading network of health care professionals specializing in the treatment and care of overweight and obese individuals. True Results' physicians, health care professionals, surgical centers, and support resources are dedicated to the LAP-BAND patient. True Results specializes in the LAP-BAND System procedure and is widely recognized as the number one provider of the procedure in the world. True Results also provides a comprehensive, multi-discipline aftercare program to ensure the success of the bariatric patient. In addition to the Surgery Center of Richardson, True Results currently has specialty surgery centers in Fort Worth, Houston, and the San Antonio/Austin area. True Results surgeons have performed more than 7,000 procedures, ensuring seasoned professionals with the experience to handle most every patient's need. For additional information on True Results and weight loss, please call 1-800-324-2694.

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